Article
Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.
Molecular and cellular biology - 1 Aug 1990
Wobbe C R, Struhl K
Abstract excerpt
We have analyzed the DNA sequence requirements for TATA element function by assaying the transcriptional activities of 25 promoters, including those representing each of the 18 single-point mutants of the consensus sequence TATAAA, in a reconstituted in vitro system that depends on the TATA eleme...
Topics
- Base Sequence
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid
- Templates, Genetic
- Transcription Factor TFIID
- Transcription Factors
- Transcription, Genetic
- Uridine Triphosphate