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Article

Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.

Molecular and cellular biology - 1 Aug 1990

Wobbe C R, Struhl K

Abstract excerpt

We have analyzed the DNA sequence requirements for TATA element function by assaying the transcriptional activities of 25 promoters, including those representing each of the 18 single-point mutants of the consensus sequence TATAAA, in a reconstituted in vitro system that depends on the TATA element-binding factor TFIID. Interestingly, yeast TFIID and HeLa cell TFIID were virtually identical in terms of their...

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Identifiers

PMID: 2196437
DOI: 10.1128/mcb.10.8.3859-3867.1990
PMCID: PMC360896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.PMID 2196437Read ↗

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