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Article

SPT20/ADA5 encodes a novel protein functionally related to the TATA-binding protein and important for transcription in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jun 1996

Roberts S M, Winston F

Abstract excerpt

Mutations selected as suppressors of Ty and solo delta insertion mutations is Saccharomyces cerevisiae have identified a number of genes important for transcription initiation. One of these gens, SPT15, encodes the TATA-binding protein, and three others, SPT3, SPT7, and SPT8, encode proteins functionally related to the TATA-binding protein. To identify additional related functions, we have selected for new spt...

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Identifiers

PMID: 8649431
DOI: 10.1128/MCB.16.6.3206
PMCID: PMC231314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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SPT20/ADA5 encodes a novel protein functionally related to the TATA-binding protein and important for transcription in Saccharomyces cerevisiae.PMID 8649431Read ↗

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription.Semantic proximity Read ↗

Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes.Semantic proximity Read ↗

Characterization of new Spt3 and TATA-binding protein mutants of Saccharomyces cerevisiae: Spt3 TBP allele-specific interactions and bypass of Spt8.Semantic proximity Read ↗

The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo.Semantic proximity Read ↗

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction.Semantic proximity Read ↗

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.Semantic proximity Read ↗

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.Semantic proximity Read ↗

TFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts allele.Semantic proximity Read ↗

Spt10-dependent transcriptional activation in Saccharomyces cerevisiae requires both the Spt10 acetyltransferase domain and Spt21.Semantic proximity Read ↗

Differential requirement of SAGA components for recruitment of TATA-box-binding protein to promoters in vivo.Semantic proximity Read ↗

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.Semantic proximity Read ↗

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