Article
Two Novel <i>Drosophila</i> TAF<sub>II</sub>s Have Homology with Human TAF<sub>II</sub>30 and Are Differentially Regulated during Development
1 Mar 2000
Abstract excerpt
TFIID is a multiprotein complex composed of the TATA binding protein (TBP) and TBP-associated factors (TAF(II)s). The binding of TFIID to the promoter is the first step of RNA polymerase II preinitiation complex assembly on protein-coding genes. Yeast (y) and human (h) TFIID complexes contain 10 to 13 TAF(II)s. Biochemical studies suggested that the Drosophila (d) TFIID complexes contain only eight TAF(II)s,...
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