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Article

Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro.

PloS one - 1 Jan 2011

Karén Jakob, Rodriguez Alejandro, Friman Tomas, Dencker Lennart, Sundberg Christian, Scholz Birger

Abstract excerpt

Microvascular pericytes are of key importance in neoformation of blood vessels, in stabilization of newly formed vessels as well as maintenance of angiostasis in resting tissues. Furthermore, pericytes are capable of differentiating into pro-fibrotic collagen type I producing fibroblasts. The present study investigates the effects of the histone deacetylase (HDAC) inhibitor valproic acid (VPA) on pericyte...

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Identifiers

PMID: 21966390
DOI: 10.1371/journal.pone.0024954
PMCID: PMC3178576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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