Article
An attempt to unify the structure of polymerases.
Protein engineering - 1 May 1990
Delarue M, Poch O, Tordo N, Moras D, Argos P
Abstract excerpt
With the great availability of sequences from RNA- and DNA-dependent RNA and DNA polymerases, it has become possible to delineate a few highly conserved regions for various polymerase types. In this work a DNA polymerase sequence from bacteriophage SPO2 was found to be homologous to the polymerase domain of the Klenow fragment of polymerase I from Escherichia coli, which is known to be closely related to those...
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