Article
Molecular diversity and catalytic activity of Thermus DNA polymerases.
Extremophiles : life under extreme conditions - 1 Sept 2009
Gibbs Moreland D, Reeves Rosalind A, Mandelman David, Mi Qingli, Lee Jun, Bergquist Peter L
Abstract excerpt
Thermus aquaticus DNA polymerase (Taq polymerase) made the polymerase chain reaction feasible and led to a paradigm shift in genomic analysis. Other Thermus polymerases were reported to have comparable performance in PCR and there was an analysis of their properties in the 1990s. We re-evaluated our earlier phylogeny of Thermus species on the basis of 16S rDNA sequences and concluded that the genus could be...
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