Article
Structural features of DNA that determine RNA polymerase II core promoter.
BMC genomics - 25 Nov 2016
Il'icheva Irina A, Khodikov Mingian V, Poptsova Maria S, Nechipurenko Dmitry Yu, Nechipurenko Yury D, Grokhovsky Sergei L
Abstract excerpt
BACKGROUND: The general structure and action of all eukaryotic and archaeal RNA polymerases machinery have an astonishing similarity despite the diversity of core promoter sequences in different species. The goal of our work is to find common characteristics of DNA region that define it as a promoter for the RNA polymerase II (Pol II). RESULTS: The profiles of a large number of physical and structural...
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