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Article

Ischemic but not pharmacological preconditioning elicits a gene expression profile similar to unprotected myocardium.

Physiological genomics - 15 Dec 2004

da Silva Rafaela, Lucchinetti Eliana, Pasch Thomas, Schaub Marcus C, Zaugg Michael

Abstract excerpt

Pharmacological (PPC) and ischemic preconditioning (IschPC) provide comparable protection against ischemia in the heart. However, the genomic phenotype may depend on the type of preconditioning. Isolated perfused rat hearts were used to evaluate transcriptional responses to PPC and IschPC in the presence (mediator/effector response) or absence (trigger response) of 40 min of test ischemia using oligonucleotide...

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Identifiers

PMID: 15494475
DOI: 10.1152/physiolgenomics.00166.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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