Article

AMPK-SIRT1 Pathway Modulates The Apoptosis, Proliferation and Migration of AR42J Cells By Regulating p53 and NF-κB

2021-06-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Acute pancreatitis (AP) is an acute abdomen caused by abnormal activation of trypsin. AMPK-SIRT1 pathway has been reported to be related to various diseases, but the function in AP remains unclear. This study is designed to investigate the mechanism and effect of AMPK-SIRT1 pathway in AP.<bold>Methods: </bold>An experimental AP model of AR42J cells was stimulate...

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Literature Corpus work: a7296bc7-c7ae-5f98-9119-e74dd92be64c
DOI: 10.21203/rs.3.rs-600516/v1

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