Article
A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element.
Molecular and cellular biology - 1 Aug 1990
Brandl C J, Struhl K
Abstract excerpt
In the gal-his3 hybrid promoter his3-GG1, the yeast upstream activator protein GCN4 stimulates transcription when bound at the position normally occupied by the TATA element. This TATA-independent activation by GCN4 requires two additional elements in the gal enhancer region that are distinct fro...
Topics
- Alleles
- Base Sequence
- Chromosome Deletion
- DNA-Binding Proteins
- Deoxyribonuclease I
- Enhancer Elements, Genetic
- Fungal Proteins
- Gene Expression Regulation
- Genes, Fungal
- Molecular Sequence Data
- Nucleosomes
- Nucleotide Mapping
- Oligonucleotide Probes
- Phenotype
- Promoter Regions, Genetic
- Protein Kinases
- Restriction Mapping
- Saccharomyces cerevisiae