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Article

TATA-binding protein activates transcription when upstream of a GCN4-binding site in a novel yeast promoter.

The Journal of biological chemistry - 15 Oct 1992

Brandl C J, Martens J A, Liaw P C, Furlanetto A M, Wobbe C R

Abstract excerpt

In the gal-his3 hybrid promoter, his3-GG1, GCN4 stimulates transcription at the position normally occupied by a TATA element. This expression requires two elements within gal1-10 sequences, a REB1-binding site and a second element, Z, which resides 20 base pairs upstream of the GCN4-binding site. No obvious TATA element is present in this promoter. To characterize the function of Z, we replaced it with short...

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Source

Identifiers

PMID: 1400410

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

TATA-binding protein activates transcription when upstream of a GCN4-binding site in a novel yeast promoter.PMID 1400410Read ↗

A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element.Semantic proximity Read ↗

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The N-terminal and C-terminal domains of RAP1 are dispensable for chromatin opening and GCN4-mediated HIS4 activation in budding yeast.Semantic proximity Read ↗

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Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites.Semantic proximity Read ↗

Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae.Semantic proximity Read ↗

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