Article
Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromodomain factor Bdf1.
Molecular cell - 2 Jul 2004
Martinez-Campa Carlos, Politis Panagiotis, Moreau Jean-Luc, Kent Nick, Goodall Jane, Mellor Jane, Goding Colin R
Abstract excerpt
Acetylation of histone tails plays a key role in chromatin dynamics and is associated with the potential for gene expression. We show here that a 2-3 bp mispositioning of the nucleosome covering the TATA box at PHO5 induces a dependency on the acetylatable lysine residues of the histone H4 N-term...
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