Article
Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation.
Molecular and cellular biology - 1 Oct 1996
Jackson B M, Drysdale C M, Natarajan K, Hinnebusch A G
Abstract excerpt
GCN4 is a transcriptional activator in the bZIP family that regulates amino acid biosynthetic genes in the yeast Saccharomyces cerevisiae. The N-terminal 100 amino acids of GCN4 contains a potent activation function that confers high-level transcription in the absence of the centrally located aci...
Topics
- Alleles
- Amino Acid Sequence
- Amino Acids
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Hydro-Lyases
- Models, Structural
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Point Mutation
- Protein Kinases
- Protein Structure, Secondary
- Recombinant Fusion Proteins
- Restriction Mapping
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins