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Article

Genetic variation, gene-expression and circulating levels of matrix metalloproteinase-9 in patients with stable coronary artery disease.

Clinica chimica acta; international journal of clinical chemistry - 18 Jan 2012

Opstad Trine B, Pettersen Alf-Aage R, Weiss Thomas W, Akra Sissel, Øvstebø Reidun, Arnesen Harald, Seljeflot Ingebjørg

Abstract excerpt

BACKGROUND: Mediators involved in atherosclerosis and plaque rupture may have importance as risk markers for coronary artery disease (CAD). We have investigated the influence of matrix metalloproteinase (MMP)-9 genetic variations on gene- and protein expression in stable CAD patients. METHODS: The promoter -1562C/T and exon 6 R279Q A/G polymorphisms were determined in 1001 patients with angiographically verified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21963461
DOI: 10.1016/j.cca.2011.09.004

Genes

CAD

Variants

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