Article
Central pulse pressure and variability in matrix metalloproteinases genes and their inhibitors in patients with ischemic heart disease.
Physiological research - 1 Jan 2014
Vašků A, Bienertová-Vašků J, Pařenica J, Pávková Goldbergová M, Novák J, Chmelíková M, Honsová D, Lipkova J, Kala P, Spinar J
Abstract excerpt
Matrix metalloproteinases (MMPs) as well as their inhibitors (TIMPs) play a crucial role in controlling extracellular matrix turnover and have recently been associated with atherosclerosis, myocardial and vascular injury. Moreover, the genetic variability of MMP genes has been suggested to play an important role in vascular remodeling and age-related arterial stiffening. This study aims to describe associations...
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