Article
Efficient translocation of positively charged residues of M13 procoat protein across the membrane excludes electrophoresis as the primary force for membrane insertion.
The EMBO journal - 1 Aug 1990
Kuhn A, Zhu H Y, Dalbey R E
Abstract excerpt
The coat protein of bacteriophage M13 is inserted into the Escherichia coli plasma membrane as a precursor protein, termed procoat, with a typical leader peptide of 23 amino acid residues. Its membrane insertion requires the electrochemical potential but not the cellular components SecA and SecY....
Topics
- Amino Acid Sequence
- Capsid
- Capsid Proteins
- Cell Membrane
- Coliphages
- Escherichia coli
- Models, Biological
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Protein Precursors
- Protein Processing, Post-Translational