Article
Involvement of SecDF and YidC in the membrane insertion of M13 procoat mutants.
Biochemistry - 9 Aug 2005
Chen Minyong, Xie Kun, Yuan Jijun, Yi Liang, Facey Sandra J, Pradel Nathalie, Wu Long-Fei, Kuhn Andreas, Dalbey Ross E
Abstract excerpt
The M13 phage Procoat protein is one of the best characterized substrates for the novel YidC pathway. It inserts into the membrane independent of the SecYEG complex but requires the 60 kDa YidC protein. Mutant Procoat proteins with alterations in the periplasmic region had been found to require SecYEG and YidC. In this report, we show that the membrane insertion of these mutants also strongly depends on SecDF...
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