Article
Functional domains of Tat required for efficient human immunodeficiency virus type 1 reverse transcription.
Journal of virology - 1 Mar 1999
Ulich C, Dunne A, Parry E, Hooker C W, Gaynor R B, Harrich D
Abstract excerpt
Tat expression is required for efficient human immunodeficiency virus type 1 (HIV-1) reverse transcription. In the present study, we generated a series of 293 cell lines that contained a provirus with a tat gene deletion (Deltatat). Cell lines that contained Deltatat and stably transfected vectors containing either wild-type tat or a number of tat mutants were obtained so that the abilities of these tat genes to...
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