Article
Silencing of human immunodeficiency virus long terminal repeat expression by an adenovirus E1a mutant.
Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1990
Ventura A M, Arens M Q, Srinivasan A, Chinnadurai G
Abstract excerpt
Gene expression from the human immunodeficiency virus (HIV) long terminal repeat (LTR) is strongly stimulated by the viral tat gene. The HIV LTR is also activated by several physical and chemical agents and heterologous viral genes, including adenovirus E1a. As E1a has separable transcriptional a...
Topics
- Adenovirus Early Proteins
- Adenoviruses, Human
- Animals
- Antigens, Viral, Tumor
- Base Sequence
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Cloning, Molecular
- Enhancer Elements, Genetic
- Gene Expression
- Genes, Viral
- HIV-1
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Oncogene Proteins, Viral
- Plasmids