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Article

Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.

Mutation research - 1 Jul 1990

Jeggo P A

Abstract excerpt

Mutants with defects in the rejoining of DNA double-strand breaks (dsbs) have been identified and characterised from E. coli and the yeast, Saccharomyces cerevisiae. More recently, 3 mammalian cell mutants with defective dsb rejoining have also been described. These mutants are xrs, XR-1 and L5178Y/S, and they are derived from at least two distinct complementation groups. The aim of this article is to review the...

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PMID: 2195330
DOI: 10.1016/0165-1110(90)90028-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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