Article
Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.
Mutation research - 1 Jul 1990
Jeggo P A
Abstract excerpt
Mutants with defects in the rejoining of DNA double-strand breaks (dsbs) have been identified and characterised from E. coli and the yeast, Saccharomyces cerevisiae. More recently, 3 mammalian cell mutants with defective dsb rejoining have also been described. These mutants are xrs, XR-1 and L517...
Topics
- Animals
- Chromosome Aberrations
- DNA
- DNA Repair
- Escherichia coli
- Mutation
- Radiation Tolerance
- Saccharomyces cerevisiae
