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Article

The QKI-PLP pathway controls SIRT2 abundance in CNS myelin.

Glia - 1 Jan 2012

Zhu H, Zhao L, Wang E, Dimova N, Liu G, Feng Y, Cambi F

Abstract excerpt

Sirtuin 2 (SIRT2), a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase expressed by oligodendrocytes (OLs), the myelin-producing cells of the central nervous system (CNS), is markedly up-regulated during active myelination (Li et al. (2007) J Neurosci 27:2606-2616; Southwood et al. (2007) Neurochem Res 32:187-195; Werner et al. (2007) J Neurosci 27:7717-7730). SIRT2 is a component of the myelin...

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Source

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Identifiers

PMID: 21948283
DOI: 10.1002/glia.21248
PMCID: PMC3217119

Genes

SIRT2
QKI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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