Article
A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C.
Hepatology (Baltimore, Md.) - 1 Oct 2009
Marcolongo Moira, Young Bradford, Dal Pero Francesca, Fattovich Giovanna, Peraro Laura, Guido Maria, Sebastiani Giada, Palù Giorgio, Alberti Alfredo
Abstract excerpt
UNLABELLED: Fibrosis progression is the main determinant of liver disease outcome in chronic hepatitis C, being influenced by environmental and host factors. Recently, a cirrhosis risk score (CRS) based on seven single-nucleotide polymorphisms was proposed as genetic predictor of cirrhosis in hepatitis C. To assess the role of CRS in predicting fibrosis progression in patients with initially no or minimal to...
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