Article
[Tm analysis method using a quenching probe is a simple and rapid way to simultaneously detect KRAS and BRAF mutations].
Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 2011
Akagi Kiwamu, Arai Yoshiko
Abstract excerpt
Epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor that, on ligand binding, triggers the RAS-RAF-MAPK signaling pathway which is mainly associated with cell proliferation. Drugs targeting EGFR have recently entered clinical practice and have proven to be effective...
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