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Article

Mutation Profile of B-Raf Gene Analyzed by fully Automated System and Clinical Features in Japanese Melanoma Patients.

Pathology oncology research : POR - 1 Jan 2017

Ide Masaru, Koba Shinichi, Sueoka-Aragane Naoko, Sato Akemi, Nagano Yuri, Inoue Takuya, Misago Noriyuki, Narisawa Yutaka, Kimura Shinya, Sueoka Eisaburo

Abstract excerpt

BRAF gene mutations have been observed in 30-50 % of malignant melanoma patients. Recent development of therapeutic intervention using BRAF inhibitors requires an accurate and rapid detection system for BRAF mutations. In addition, the clinical characteristics of the melanoma associated with BRAF mutations in Japanese patients have not been investigated on a large scale evaluation. We recently established...

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Identifiers

PMID: 27766572
DOI: 10.1007/s12253-016-0121-2

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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