Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients.

Pathology oncology research : POR - 1 Oct 2017

Hosoya Kazuhisa, Matsusaka Satoshi, Kashiwada Tomomi, Suzuki Koichi, Ureshino Norio, Sato Akemi, Miki Yoshio, Kitera Kazuki, Hirai Mitsuharu, Hatake Kiyohiko, Kimura Shinya, Sueoka-Aragane Naoko

Abstract excerpt

KRAS mutations have been recognized as predictive markers of primary resistance to anti-EGFR-antibodies in colorectal cancer patients. In addition, newly detected KRAS mutations have been reported to be related with acquired resistance to chemotherapy containing anti-EGFR antibody. Considering this evidence, monitoring of KRAS mutations is indispensable for making treatment decisions, and the method should be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circulating Tumor DNA
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to KRAS gene

Share to MBP gene

Share to Mutation

Share to Polymerase Chain Reaction

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 28058585
DOI: 10.1007/s12253-016-0175-1

Genes

KRAS
EGFR
MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients.PMID 28058585Read ↗

A fully integrated, automated and rapid detection system for KRAS mutations.Semantic proximity Read ↗

Enhanced asymmetric blocked qPCR method for affordable detection of point mutations in KRAS oncogene.Semantic proximity Read ↗

Asymmetric mutant-enriched polymerase chain reaction and quantitative DNA melting analysis of KRAS mutation in colorectal cancer.Semantic proximity Read ↗

A noninvasive system for monitoring resistance to epidermal growth factor receptor tyrosine kinase inhibitors with plasma DNA.Semantic proximity Read ↗

PCR-based assays versus direct sequencing for evaluating the effect of KRAS status on anti-EGFR treatment response in colorectal cancer patients: a systematic review and meta-analysis.Semantic proximity Read ↗

Rapid Multiplex Strip Test for the Detection of Circulating Tumor DNA Mutations for Liquid Biopsy Applications.Semantic proximity Read ↗

Eprobe-mediated screening system for somatic mutations in the KRAS locus.Semantic proximity Read ↗

[Tm analysis method using a quenching probe is a simple and rapid way to simultaneously detect KRAS and BRAF mutations].Semantic proximity Read ↗

A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection.Semantic proximity Read ↗

Sensitive detection of KRAS mutations in archived formalin-fixed paraffin-embedded tissue using mutant-enriched PCR and reverse-hybridization.Semantic proximity Read ↗

[High-throughput screening method of KRAS mutations at codons 12 and 13 in formalin-fixed paraffin-embedded tissue specimens of metastatic colorectal cancer].Semantic proximity Read ↗

Performance of KRAS mutation detection in plasma exosomes from patients with early-stage colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.