Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic mutations of caspase-2 gene in gastric and colorectal cancers.

Pathology, research and practice - 15 Oct 2011

Kim Min Sung, Kim Ho Shik, Jeong Eun Goo, Soung Young Hwa, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

There is mounting evidence that evasion of apoptosis is a hallmark of cancer. Caspase-2, which plays roles in both extrinsic and intrinsic apoptosis pathways, is considered a candidate tumor suppressor. The aim of this study was to explore the possibility that genetic alterations of caspase-2 gene are present in human cancers. In this study, we analyzed the entire coding sequences of human caspase-2 gene for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Aged, 80 and over
Share to Apoptosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to DNA Mutational Analysis

Share to Neoplasm Staging

Share to Polymorphism, Single-Stranded Conformational

Share to Stomach Neoplasms

Source

Identifiers

PMID: 21940110
DOI: 10.1016/j.prp.2011.08.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic mutations of caspase-2 gene in gastric and colorectal cancers.PMID 21940110Read ↗

CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas.Semantic proximity Read ↗

Mutational analysis of the CASP6 gene in colorectal and gastric carcinomas.Semantic proximity Read ↗

Inactivating mutations of caspase-8 gene in colorectal carcinomas.Semantic proximity Read ↗

Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.Semantic proximity Read ↗

Inactivating mutations of CASPASE-7 gene in human cancers.Semantic proximity Read ↗

Inactivating mutations of the caspase-10 gene in gastric cancer.Semantic proximity Read ↗

Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas.Semantic proximity Read ↗

Mutational analysis of CASP10 gene in colon, breast, lung and hepatocellular carcinomas.Semantic proximity Read ↗

Somatic mutations of CASP3 gene in human cancers.Semantic proximity Read ↗

Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer.Semantic proximity Read ↗

A tumor suppressor function for caspase-2Semantic proximity Read ↗

Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.