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Inactivating mutations of the caspase-10 gene in gastric cancer.

Oncogene - 25 Apr 2002

Park Won Sang, Lee Jong Heun, Shin Min Sun, Park Jik Young, Kim Hong Sug, Lee Jong Ho, Kim Young Sil, Lee Shi Nae, Xiao Wenhua, Park Cho Hyun, Lee Sug Hyung, Yoo Nam Jin, Lee Jung Young

Abstract excerpt

We have analysed the genetic alteration of the entire coding region and all splice sites of caspase-8 and -10 genes in 99 gastric cancers by polymerase chain reaction (PCR)-single strand conformation polymorphism (SSCP) and sequencing. We found LOH of the caspase-8 and -10 in nine (28%) of 32 and in four (15%) of 26 informative cases, respectively. Overall, three of 99 gastric cancers (3%) were found to have the...

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PMID: 11973654
DOI: 10.1038/sj.onc.1205394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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