Article
Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults.
Journal of human genetics - 1 Dec 2011
Curocichin Ghenadie, Wu Ying, McDade Thomas W, Kuzawa Christopher W, Borja Judith B, Qin Li, Lange Ethan M, Adair Linda S, Lange Leslie A, Mohlke Karen L
Abstract excerpt
C-reactive protein (CRP) is a component of nonspecific immune defense and is a reliable marker of low-grade inflammation involved in obesity, type 2 diabetes and cardiovascular disease. Genome-wide association studies in middle-aged and elderly populations, predominantly of European descent, demonstrated associations of CRP levels with single-nucleotide polymorphisms (SNPs) at several loci. To examine whether the...
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