Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.

BMC medical genetics - 24 Sept 2011

Middelberg Rita P S, Ferreira Manuel A R, Henders Anjali K, Heath Andrew C, Madden Pamela A F, Montgomery Grant W, Martin Nicholas G, Whitfield John B

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have become a major strategy for genetic dissection of human complex diseases. Analysing multiple phenotypes jointly may improve both our ability to detect genetic variants with multiple effects and our understanding of their common features. Allelic associations for multiple biochemical traits (serum alanine aminotransferase, aspartate aminotransferase,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 2',5'-Oligoadenylate Synthetase
Share to Apolipoprotein C-I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein C-II

Share to Apolipoproteins C

Share to Cardiovascular Diseases

Share to Diseases in Twins

Share to Lipoprotein Lipase

Share to Mitochondrial Precursor Protein Import Complex Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21943158
DOI: 10.1186/1471-2350-12-123
PMCID: PMC3189113

Genes

CRP
APOE
LPL
OASL
TOMM40
BCHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.PMID 21943158Read ↗

Identification of genetic loci simultaneously associated with multiple cardiometabolic traits.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.Semantic proximity Read ↗

Defining the spectrum of alleles that contribute to blood lipid concentrations in humans.Semantic proximity Read ↗

Common variants at 30 loci contribute to polygenic dyslipidemia.Semantic proximity Read ↗

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.Semantic proximity Read ↗

Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.Semantic proximity Read ↗

COVID-19 enters the expanding network of apolipoprotein E4-related pathologies.Semantic proximity Read ↗

Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults.Semantic proximity Read ↗

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.Semantic proximity Read ↗

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.Semantic proximity Read ↗

Evaluation of seven common lipid associated loci in a large Indian sib pair study.Semantic proximity Read ↗

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.