Article
MIG-15 and ERM-1 promote growth cone directional migration in parallel to UNC-116 and WVE-1.
Development (Cambridge, England) - 1 Oct 2011
Teulière Jérôme, Gally Christelle, Garriga Gian, Labouesse Michel, Georges-Labouesse Elisabeth
Abstract excerpt
Neurons require precise targeting of their axons to form a connected network and a functional nervous system. Although many guidance receptors have been identified, much less is known about how these receptors signal to direct growth cone migration. We used Caenorhabditis elegans motoneurons to study growth cone directional migration in response to a repellent UNC-6 (netrin homolog) guidance cue. The...
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