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Article

Uncovering specific genetic-respiratory disease endotypes for rheumatoid arthritis risk.

Annals of the rheumatic diseases - 1 Feb 2025

Kronzer Vanessa L, Williamson Katrina A, Hayashi Keigo, Atkinson Elizabeth J, Crowson Cynthia S, Wang Xiaosong, Cui Jing, Cerhan James R, Sletten Jennifer A, McDermott Gregory C, Joerns Elena K, Vassallo Robert, Davis John M, Sparks Jeffrey A

Abstract excerpt

OBJECTIVE: We aimed to identify specific genetic-respiratory disease endotypes for rheumatoid arthritis (RA) risk. METHODS: This case-control study used the Mass General Brigham (MGB) and Mayo Clinic (MC) Biobanks for discovery and replication, respectively. We matched criteria-confirmed incident RA cases to four non-RA controls on age, sex and health record history. Genetic exposures included the top 11 RA risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39919896
DOI: 10.1136/ard-2024-226391
PMCID: PMC11822224

Genes

FAM167A
NFKBIE

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