Article
Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history.
Annals of the rheumatic diseases - 1 Aug 2015
Sparks Jeffrey A, Chen Chia-Yen, Jiang Xia, Askling Johan, Hiraki Linda T, Malspeis Susan, Klareskog Lars, Alfredsson Lars, Costenbader Karen H, Karlson Elizabeth W
Abstract excerpt
OBJECTIVE: To develop and validate rheumatoid arthritis (RA) risk models based on family history, epidemiologic factors and known genetic risk factors. METHODS: We developed and validated models for RA based on known RA risk factors, among women in two cohorts: the Nurses' Health Study (NHS, 381 RA cases and 410 controls) and the Epidemiological Investigation of RA (EIRA, 1244 RA cases and 971 controls). Model...
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