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Article

Protocadherin-1 polymorphisms are associated with eczema in two Dutch birth cohorts.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 May 2012

Koning Henk, Postma Dirkje S, Brunekreef Bert, Duiverman Eric J, Smit Henriette A, Thijs Carel, Penders John, Kerkhof Marjan, Koppelman Gerard H

Abstract excerpt

BACKGROUND: Eczema and asthma share a common genetic background and show linkage to chromosome 5q31-33. Protocadherin-1 (PCDH1) is located in this region and was identified as a susceptibility gene for bronchial hyper-responsiveness (BHR), a hallmark of asthma. PCDH1 encodes an adhesion molecule, expressed in airway and skin epithelium. We determined whether PCDH1 polymorphisms, previously associated with asthma...

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Source

Identifiers

PMID: 21929597
DOI: 10.1111/j.1399-3038.2011.01201.x

Genes

PCDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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