Article

A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies <i>ANXA1</i> as a susceptibility locus for persistent wheezing

2023-03-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Many genes associated with asthma explain only a fraction of its heritability. Most genome-wide association studies (GWASs) used a broad definition of “doctor-diagnosed asthma”, thereby diluting genetic signals by not considering asthma heterogeneity. The objective of our study was to identify genetic associates of childhood wheezing phenotypes. <h4>Methods</h4> We conducte...

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Literature Corpus work: 58b1f66a-03e9-53cd-866e-397af574a466
DOI: 10.1101/2023.03.03.23284449

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