Article
Role of the GNAS1 T393C polymorphism in patients with glioblastoma multiforme.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Nov 2011
El Hindy N, Lambertz N, Bachmann H S, Frey U H, Adamzik M, Zhu Y, Sure U, Siffert W, Sandalcioglu I E
Abstract excerpt
The T393C polymorphism of the GNAS1 locus, which encodes the Gαs protein, has recently been found to be associated with patient outcome in various malignancies. We investigated the association between GNAS1 genotype and survival among patients suffering from glioblastoma multiforme (GBM). One hundred and sixty-two patients with GBM were retrospectively investigated. Inclusion criteria were availability of DNA...
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