Article
Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiforme.
Journal of cancer research and clinical oncology - 1 Sept 2010
El Hindy Nicolai, Adamzik Michael, Lambertz Nicole, Bachmann Hagen S, Worm Karl, Egensperger Rupert, Frey Ulrich H, Asgari Siamak, Sure Ulrich, Siffert Winfried, Sandalcioglu I Erol
Abstract excerpt
PURPOSE: Genotypes of the C825T polymorphism of the GNB3 gene encoding the G protein beta3 subunit were recently associated with the prognosis of different malignomas. We investigated potential associations of GNB3 genotypes with survival of patients with glioblastoma multiforme (GBM). METHODS: One hundred and sixty-one patients suffering from GBM were retrospectively investigated. Inclusion criteria were...
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