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Article

A novel functional polymorphism of GFAP decrease glioblastoma susceptibility through inhibiting the binding of miR-139.

Aging - 10 May 2018

Wang Jie, Wang Ming-Lei, Wang Chang-Hui, Sun Shu-Yan, Zhang Han-Bing, Jiang Yang-Yang, Xu Qi-Wu, Wang Ying, Gu Shi-Xin

Abstract excerpt

Glioblastoma (GBM) is the most commonly diagnosed solid tumor outside the central nervous system. However, genetic factors underlying GBM remain largely unclear. Previous studies indicated that Glial fibrillary acidic protein (GFAP) might play an important role in the aggressiveness of GBM and also contributed to its poor overall survival. The present study aims to test (1) the associations between GFAP single...

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Identifiers

PMID: 29746255
DOI: 10.18632/aging.101442
PMCID: PMC5990380

Genes

GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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