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Article

The functional Aquaporin 1 -783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme.

Journal of surgical oncology - 1 Dec 2013

El Hindy Nicolai, Rump Katharina, Lambertz Nicole, Zhu Yuan, Frey Ulrich H, Bankfalvi Agnes, Siffert Winfried, Sure Ulrich, Peters Jürgen, Adamzik Michael, Sandalcioglu I Erol

Abstract excerpt

BACKGROUND: Despite a dismal prognosis, variability exists regarding the survival-time in patients with glioblastoma-multiforme (GBM), which may be explained by genetic variation. A possible candidate-gene for such variation is Aquaporin-1 (AQP1), since Aquaporin-1-expression influences the pathogenesis and outcome of various malignancies. Functional genetic variants in the promoter of AQP1, modifying...

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Identifiers

PMID: 24014128
DOI: 10.1002/jso.23421

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AQP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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