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Article

VEGF gene polymorphisms in Iranian patients with intracranial glioblastoma.

Journal of neurosurgical sciences - 1 Oct 2024

Hanaei Sara, Mojtahedi Hanieh, Namvar Mohamad, Iranmehr Arad, Safaei Reyhaneh, Razavi Azadehsadat, Esmaeili Marzie, Sadr Maryam, Rezaei Arezou, Edalatfar Maryam, Khayat Kashani Hamidreza, Sadeghi-Naini Mohsen, Darbeheshti Farzaneh, Gharehdaghi Jaber, Forouzesh Mehdi, Ebrahimi Abdolali, Rezaei Nima

Abstract excerpt

BACKGROUND: Glioblastoma is one of the most common malignant brain tumors in adults with poor prognosis. Neovascularization is one of the characteristics of these tumors, which is associated with overexpression of vascular endothelial growth factor (VEGF). Accordingly, single nucleotide polymorphisms of this gene could play an important role in structural and functional alterations leading to overexpression of...

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PMID: 36651322
DOI: 10.23736/S0390-5616.22.05832-5

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