Article
Vitamin K requirement and reproduction in bromadiolone-resistant Norway rats.
Pest management science - 1 Mar 2012
Jacob Jens, Endepols Stefan, Pelz Hans-Joachim, Kampling Engelbert, Cooper Trevor G, Yeung Ching Hei, Redmann Klaus, Schlatt Stefan
Abstract excerpt
BACKGROUND: Nucleotide polymorphisms in the VKORC1 gene can be linked to anticoagulant rodenticide resistance in Norway rats (Rattus norvegicus Berkenhout). This provides a fitness advantage to rats exposed to anticoagulant actives, but may also cause fitness costs. The vitamin K requirement and reproductive parameters of bromadiolone-resistant rats (Westphalian resistant strain; VKOR variant Tyr139Cys) and...
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