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Article

The genetic basis of resistance to anticoagulants in rodents.

Genetics - 1 Aug 2005

Pelz Hans-Joachim, Rost Simone, Hünerberg Mirja, Fregin Andreas, Heiberg Ann-Charlotte, Baert Kristof, MacNicoll Alan D, Prescott Colin V, Walker Anne-Sophie, Oldenburg Johannes, Müller Clemens R

Abstract excerpt

Anticoagulant compounds, i.e., derivatives of either 4-hydroxycoumarin (e.g., warfarin, bromadiolone) or indane-1,3-dione (e.g., diphacinone, chlorophacinone), have been in worldwide use as rodenticides for >50 years. These compounds inhibit blood coagulation by repression of the vitamin K reductase reaction (VKOR). Anticoagulant-resistant rodent populations have been reported from many countries and pose a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15879509
DOI: 10.1534/genetics.104.040360
PMCID: PMC1449767

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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