Article
Distribution of VKORC1 single nucleotide polymorphism in wild Rattus norvegicus in France.
Pest management science - 1 Mar 2010
Grandemange Agnes, Lasseur Romain, Longin-Sauvageon Christiane, Benoit Etienne, Berny Philippe
Abstract excerpt
BACKGROUND: Anticoagulant rodenticides are commonly used to control rodent pests all over the world. These pesticides inhibit one enzyme of the vitamin K cycle, Vkorc1, and thus prevent blood clotting and cause death by haemorrhage. Resistance to anticoagulants was first observed in Scotland in 1958, and more potent anticoagulants have been developed to overcome this obstacle. Unfortunately, these chemicals are...
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