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Article

Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant.

Yeast (Chichester, England) - 1 Nov 2011

Smith Sarah B, Kiss Daniel L, Turk Edward, Tartakoff Alan M, Andrulis Erik D

Abstract excerpt

Subunits of the RNA processing exosome assemble into structurally distinct protein complexes that function in disparate cellular compartments and RNA metabolic pathways. Here, in a genetic, cell biological and transcriptomic analysis, we examined the role of Dis3, an essential polypeptide with endo- and 3'→5' exo-ribonuclease activity, in cell cycle progression. We present several lines of evidence that...

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Share to Cell Cycle
Share to Exoribonucleases
Share to Exosome Multienzyme Ribonuclease Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mitosis

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Source

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Identifiers

PMID: 21919057
DOI: 10.1002/yea.1899
PMCID: PMC3367412

Genes

DIS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant.PMID 21919057Read ↗

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The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human DiseaseSemantic proximity Read ↗

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Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility.Semantic proximity Read ↗

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