Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cross-species transcriptomics identifies obesity associated genes between human and mouse studies

25 Jun 2024

Abstract excerpt

BACKGROUND: Fundamentally defined by an imbalance in energy consumption and energy expenditure, obesity is a significant risk factor of several musculoskeletal conditions including osteoarthritis (OA). High-fat diets and sedentary lifestyle leads to increased adiposity resulting in systemic inflammation due to the endocrine properties of adipose tissue producing inflammatory cytokines and adipokines. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Osteoarthritis Treatment and Mechanisms
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38918843
DOI: 10.1186/s12967-024-05414-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cross-species transcriptomics identifies obesity associated genes between human and mouse studiesPMID 38918843Read ↗

A conserved transcriptomic model defines metabolic resilience and vulnerability in obesitySemantic proximity Read ↗

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesitySemantic proximity Read ↗

Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine modelSemantic proximity Read ↗

Uncovering causal genetic mediators linking redefined obesity to osteoarthritis: Multidimensional analysis from population to genetic mechanisms.Semantic proximity Read ↗

Microarray Based Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with HumanSemantic proximity Read ↗

Obesity Gene Atlas in MammalsSemantic proximity Read ↗

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.Semantic proximity Read ↗

The metabolic response to a high-fat diet reveals obesity-prone and -resistant phenotypes in mice with distinct mRNA-seq transcriptome profiles.Semantic proximity Read ↗

Common and ethnic-specific derangements in skeletal muscle transcriptome associated with obesity.Semantic proximity Read ↗

A novel computational framework to identify translational potential of genetic mouse models in rare genetic obesitySemantic proximity Read ↗

A Stratified Transcriptomics Analysis of Polygenic Fat and Lean Mouse Adipose Tissues Identifies Novel Candidate Obesity GenesSemantic proximity Read ↗

Transcriptome analysis of the adipose tissue in a mouse model of metabolic syndrome identifies gene signatures related to disease pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.