Article

A conserved transcriptomic model defines metabolic resilience and vulnerability in obesity

2026-05-22

Abstract excerpt

<h4>Background</h4> Obesity arises from a complex interplay of genetic and environmental factors, with alterations of transcriptional networks that integrate metabolic, immune, and regulatory pathways. Conventional measures such as body mass index (BMI) quantify body size but fail to capture the molecular heterogeneity underlying divergent metabolic outcomes. We therefore sought to construct a gene expression-bas...

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Literature Corpus work: d8550eaa-874f-5075-9e03-c3b9444eab8f
DOI: 10.64898/2026.05.20.726524

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