Article
Recessively inherited deficiencies predisposing to cancer.
Anticancer research - 1 Jan 2000
Müller H
Abstract excerpt
The genetic factors involved in the multistep process of carcinogenesis can be divided at least into two major categories: 1. Mutated or lost genes, which may directly represent one step in the sequential process (tumour suppressor genes); inheritance of one tumour suppressor gene causes dominant expression of the carcinogenic phenotype (the dominant inheritance is described in the accompanying paper); 2. Other...
Topics
- DNA Repair
- Genes, Recessive
- Humans
- Immunologic Deficiency Syndromes
- Mutation
- Neoplasms
- Werner Syndrome