Article
Beta-adrenergic receptor polymorphisms associated with length of ICU stay in pediatric status asthmaticus.
Pediatric pulmonology - 1 Mar 2012
Carroll Christopher L, Sala Kathleen A, Zucker Aaron R, Schramm Craig M
Abstract excerpt
BACKGROUND: During severe exacerbations, asthmatic children vary significantly in their response to high-dose continuous β(2) -adrenergic receptor (ADRβ(2) ) agonist therapy. Genetic polymorphisms have been identified within the ADRβ(2) that may be functionally relevant, but few studies have been performed in this population. Our hypothesis was that genotypic differences are associated with magnitude of response...
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