Article
Asthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphism.
Thorax - 1 Sept 2000
Taylor D R, Drazen J M, Herbison G P, Yandava C N, Hancox R J, Town G I
Abstract excerpt
BACKGROUND: Polymorphisms of the beta(2) adrenoceptor influence receptor function in vitro and asthma phenotypes in vivo. However, their importance in determining responses to inhaled beta agonist treatment has not been clearly defined. METHODS: In a retrospective analysis of previously published data we have examined relationships between polymorphisms at codons 16 and 27 of the beta(2) adrenoceptor and clinical...
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