Article
Higher frequency of premature stop codon mutations at vpu gene of human immunodeficiency virus type 1 CRF01_AE compared with those of other subtypes.
Microbes and infection - 1 Feb 2005
Komoto Satoshi, Tsuji Shoutaro, Lee Byong-Jae, Iwabu Yukie, Kojima Yoko, Otake Toru, Taniguchi Koki, Ikuta Kazuyoshi
Abstract excerpt
Our previous study demonstrated the anti-apoptosis function of the human immunodeficiency virus type 1 (HIV-1) vpu gene product in normal CD4+ T lymphocytes. In this study, using sequences obtained from the HIV sequence database, we compared vpu sequences from 184 preparations of various subtypes of HIV-1 from diverse geographical regions. Our analysis revealed that CRF01_AE isolates had premature stop codon...
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