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Article

HIV1 V3 loop hypermutability is enhanced by the guanine usage bias in the part of env gene coding for it.

In silico biology - 1 Jan 2009

Khrustalev Vladislav Victorovich

Abstract excerpt

Guanine is the most mutable nucleotide in HIV genes because of frequently occurring G to A transitions, which are caused by cytosine deamination in viral DNA minus strands catalyzed by APOBEC enzymes. Distribution of guanine between three codon positions should influence the probability for G to...

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PMID: 20109155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20109155-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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